Prosthetic limbs gain realistic feel through advanced brain-computer interface research

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Katherine Baicker Provost | The University of Chicago

Prosthetic limbs gain realistic feel through advanced brain-computer interface research

Researchers from several universities, including the University of Chicago, have made significant strides in developing brain-computer interfaces that enhance the tactile experience of prosthetic limbs. This technology aims to restore both motor control and sensation for individuals who have lost limb function.

Charles Greenspon, a neuroscientist at the University of Chicago, explained the importance of touch in everyday tasks. "Most people don’t realize how often they rely on touch instead of vision—typing, walking, picking up a flimsy cup of water," he said. The research team has published their findings in Nature Biomedical Engineering and Science, focusing on direct electrical stimulation of the brain to recreate tactile feedback.

The project involves collaboration among scientists and engineers from UChicago, the University of Pittsburgh, Northwestern University, Case Western Reserve University, and Blackrock Neurotech. Their approach uses electrode arrays implanted in brain areas responsible for hand movement and sensation. This allows participants to move robotic arms by thought and receive sensory feedback through electrical pulses.

For about ten years, this method could only provide basic contact sensations. Greenspon noted that previous efforts resulted in weak signals that were difficult to localize on the hand. However, recent studies have overcome these limitations.

In one study published in Nature Biomedical Engineering, researchers focused on ensuring stable and accurately localized touch sensations. By delivering short pulses to electrodes and mapping corresponding brain areas, they found that stimulating closely spaced electrodes together produced stronger sensations.

"If I stimulate an electrode on day one and a participant feels it on their thumb," Greenspon said, "we can test that same electrode on day 100 or even many years later." This consistency is crucial for any clinical device intended for daily use.

A complementary study published in Science explored making artificial touch more immersive by creating overlapping sensory locations using pairs or clusters of electrodes. Participants reported feeling gliding touches over their fingers due to sequential activation patterns.

The research aims to improve independence and quality of life for those with limb loss or paralysis. "We all care about the people in our lives who get injured and lose the use of a limb — this research is for them," Greenspon emphasized.

Future developments may include finer coverage across the hand as electrode designs advance. Robert Gaunt from the University of Pittsburgh stated: "We hope to integrate the results into our robotics systems."

These advancements could also benefit individuals with other types of sensory loss. The team has collaborated with UChicago surgeons on projects like the Bionic Breast Project aimed at restoring touch after mastectomy.

Despite challenges ahead, these studies offer hope for prosthetics that provide not just functionality but also sensory experiences akin to natural limbs.

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